2009年10月29日

The inside story on place cells

Neurons known as place cells encode spatial information that is needed to guide an animal's movement.

Nearly 40 years after these cells were discovered, neuroscience gets a look at their internal dynamics.


On page 941 (see page of this issue, Haevey et al.(Harvey,c.d.,Collman,F.,Do,bec,D.A.&Tank,D.W. Nature 461,941-946/2009) deecribe a novel combination of techniques that they have used to address unresolved questions about brain function.

The experiments involve mice navigating within a virtual-reality setting while intracellular electrophysiological recordingsare made of particular neurons ― pyramidal neurons ― in the hippocampus.

The ability to gather such data adds greatly to the information thatcan be glened from the accompanying extracellular recordings.


### DataBace ###
nature Vol.461 837-1018 Issue no.7266 15 Octiber 2009
Article p.941 / Intracellular dynamics of hippocampal place cells during virtual navigation / C D Harvey et al. (Princeton University)
News and Views p.889 / Neuro Science : The insade story on place cells / Douglas Niz


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